Alexander Y. Maslov, M.D., Ph.D

Research Assistant Professor.

 

Email: alex.maslov at einstein.yu.edu

 

 

Education

 

Ph.D.  Cell biology/Biochemistry, Voronezh State University, Russia, 1996

 

M.D.  Voronezh State Medical Academy named after N.N. Burdenko, Russia, 1992

Research interests

 

 

 

Publications

 

  1. Peterson EA, Polgar Z, Devakanmalai GS, Li Y, Jaber FL, Zhang W, Wang X, Iqbal NJ, Murray JW, Roy-Chowdhury N, Quispe-Tintaya W, Maslov AY, Tchaikovskaya TL, Sharma Y, Rogler LE, Gupta S, Zhu L, Roy-Chowdhury J, Shafritz DA. Genes and Pathways Promoting Long-Term Liver Repopulation by Ex Vivo hYAP-ERT2 Transduced Hepatocytes and Treatment of Jaundice in Gunn Rats. Hepatology communications. 2019; 3(1):129-146.

  2. Solodskikh SA, Panevina AV, Gryaznova MV, Gureev AP, Serzhantova OV, Mikhailov AA, Maslov AY, Popov VN. Targeted sequencing to discover germline variants in the BRCA1 and BRCA2 genes in a Russian population and their association with breast cancer risk.

  3. Quispe-Tintaya W, Lee M, Dong X, Weiser DA, Vijg J, Maslov AY. Bleomycin-induced genome structural variations in normal, non-tumor cells. Scientific reports. 2018; 8(1):16523.

  4. Miller EM, Patterson NE, Zechmeister JM, Bejerano-Sagie M, Delio M, Patel K, Ravi N, Quispe-Tintaya W, Maslov A, Simmons N, Castaldi M, Vijg J, Karabakhtsian RG, Greally JM, Kuo DYS, Montagna C. Development and validation of a targeted next generation DNA sequencing panel outperforming whole exome sequencing for the identification of clinically relevant genetic variants. Oncotarget. 2017; 8(60):102033-102045.

  5. Bashmakov VY, Gorbacheva TM, Panevina AV, Solodskikh SA, Moshurov IP, Mikhaylov AA, Maslov AY, Popov VN. Changes in levels of metabolic pathway gene expression under conditions of clear cell renal carcinoma. Doklady. Biochemistry and biophysics. 2017; 474(1):159-161.

  6. Dong X, Zhang L, Milholland B, Lee M, Maslov AY, Wang T, Vijg J. Accurate identification of single-nucleotide variants in whole-genome-amplified single cells. Nature methods. 2017; 14(5):491-493. NIHMSID: NIHMS855609

  7. Andriani GA, Almeida VP, Faggioli F, Mauro M, Tsai WL, Santambrogio L, Maslov A, Gadina M, Campisi J, Vijg J, Montagna C. Whole Chromosome Instability induces senescence and promotes SASP. Scientific reports. 2016; 6:35218.

  8. Quispe-Tintaya W, Gorbacheva T, Lee M, Makhortov S, Popov VN, Vijg J, Maslov AY. Quantitative detection of low-abundance somatic structural variants in normal cells by high-throughput sequencing. Nature methods. 2016; 13(7):584-6. NIHMSID: NIHMS786842

  9. Delio M, Patel K, Maslov A, Marion RW, McDonald TV, Cadoff EM, Golden A, Greally JM, Vijg J, Morrow B, Montagna C. Development of a Targeted Multi-Disorder High-Throughput Sequencing Assay for the Effective Identification of Disease-Causing Variants. PloS one. 2015; 10(7):e0133742.

  10. Maslov AY, Quispe-Tintaya W, Gorbacheva T, White RR, Vijg J. High-throughput sequencing in mutation detection: A new generation of genotoxicity tests? Mutation research. 2015; 776:136-43. NIHMSID: NIHMS683341

  11. White RR, Milholland B, de Bruin A, Curran S, Laberge RM, van Steeg H, Campisi J, Maslov AY, Vijg J. Controlled induction of DNA double-strand breaks in the mouse liver induces features of tissue ageing. Nature communications. 2015; 6:6790. NIHMSID: NIHMS668517

  12. Gorbacheva T, Quispe-Tintaya W, Popov VN, Vijg J, Maslov AY. Improved transposon-based library preparation for the Ion Torrent platform. BioTechniques. 2015; 58(4):200-2. NIHMSID: NIHMS865960

  13. Quispe-Tintaya W, White RR, Popov VN, Vijg J, Maslov AY. Rapid mitochondrial DNA isolation method for direct sequencing. Methods in molecular biology (Clifton, N.J.). 2015; 1264:89-95.

  14. Quispe-Tintaya W, White RR, Popov VN, Vijg J, Maslov AY. Fast mitochondrial DNA isolation from mammalian cells for next-generation sequencing. BioTechniques. 2013; 55(3):133-6. NIHMSID: NIHMS665311

  15. Maslov AY, Ganapathi S, Westerhof M, Quispe-Tintaya W, White RR, Van Houten B, Reiling E, Dollé ME, van Steeg H, Hasty P, Hoeijmakers JH, Vijg J. DNA damage in normally and prematurely aged mice. Aging cell. 2013; 12(3):467-77. NIHMSID: NIHMS455818

  16. Maslov AY, Lee M, Gundry M, Gravina S, Strogonova N, Tazearslan C, Bendebury A, Suh Y, Vijg J. 5-aza-2'-deoxycytidine-induced genome rearrangements are mediated by DNMT1. Oncogene. 2012; 31(50):5172-9. NIHMSID: NIHMS347163

  17. Maslov AY, Metrikin M, Vijg J. A dual-activation, adenoviral-based system for the controlled induction of DNA double-strand breaks by the restriction endonuclease SacI. BioTechniques. 2009; 47(4):847-54. NIHMSID: NIHMS668275

  18. Maslov AY, Vijg J. Genome instability, cancer and aging. Biochimica et biophysica acta. 2009; 1790(10):963-9. NIHMSID: NIHMS668287

  19. Vijg J, Maslov AY, Suh Y. Aging: a sirtuin shake-up? Cell. 2008; 135(5):797-8.

  20. Maslov AY, Bailey KJ, Mielnicki LM, Freeland AL, Sun X, Burhans WC, Pruitt SC. Stem/progenitor cell-specific enhanced green fluorescent protein expression driven by the endogenous Mcm2 promoter. Stem cells (Dayton, Ohio). 2007; 25(1):132-8.

  21. Bailey KJ, Maslov AY, Pruitt SC. Accumulation of mutations and somatic selection in aging neural stem/progenitor cells. Aging cell. 2004; 3(6):391-7.

  22. Pruitt SC, Bussman A, Maslov AY, Natoli TA, Heinaman R. Hox/Pbx and Brn binding sites mediate Pax3 expression in vitro and in vivo. Gene expression patterns : GEP. 2004; 4(6):671-85.

  23. Maslov AY, Barone TA, Plunkett RJ, Pruitt SC. Neural stem cell detection, characterization, and age-related changes in the subventricular zone of mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2004; 24(7):1726-33.

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